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If CRP dropped meaningfully (e.g., from 2.5 to 1.0), the protocol is working at a systemic level

Some people alternate between the two medications over time, using semaglutide for maintenance and tirzepatide for periods when they need additional weight loss

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ACTH then stimulates the adrenal gland to release glucocorticoids, which possess various downstream physiological properties

This raises questions about whether this intake was representative of their usual diet