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1 Stored primarily in the liver, vitamin B12 plays an important role in several essential bodily functions, including: 2 DNA synthesis Healthy red blood cell formation Central nervous system development and function Enzyme function Interest in vitamin B12s role in long-term health has grown in recent years not only because it helps support neuron function, learning, and memory, but also because some research has explored whether elevated vitamin B12 levels may be associated with certain cancers

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OPTION-DM was a multicentre, randomised, double-blind, crossover trial in patients with DPN

encoded by the HSD11B1 gene) being particularly important