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This review is focused on the inhibition of GSTs, in particular GSTP1-1, as a potential therapeutic approach for the treatment of cancer and other diseases associated with aberrant cell proliferation

Additionally, disulfide compounds such as disulfiram (DSF) and fursultiamine disrupt the GPX4-HSC70 interaction, inhibiting GPX4 degradation and enhancing ferroptosis resistance [84]

Nonetheless, the results of this study confirmed the clinical effectiveness of topical tranexamic acid with a significant reduction in average MASI scores after 12 weeks of treatment

Cysteine is the limiting amino acid for the bodys synthesis of glutathione so it does make sense that oral NAC can increase cellular levels