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Cisplatin accumulates persistently in the mitochondria of energy metabolism-related organs (skeletal muscle, liver), forms platinum-mtDNA adducts to disrupt mitochondrial structure and function, and causes oxidative phosphorylation impairment and insufficient ATP production, ultimately driving persistent fatigue (Huot et al

Human evidence is limited to early-phase ulcerative colitis trial work under the PL 14736 designation

LC3 mediates mitophagy for hair regeneration To explore how LC3 affects hair regeneration, we treated the backs of 7-week-old shaved mice with a small molecule that can activate LC3

Five-year actual overall survival in resected pancreatic cancer: a contemporary single-institution experience from a multidisciplinary perspective

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