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For example, neurexin-1 and LRRTM4 bind in a Ca 2+ -dependent manner [61], which may suggest that synaptic adhesion molecules can sense synaptic activity (Ca 2+ release) and thereby cause a change in protein structure to form a protein conformation for binding by both pre- and postsynaptic adhesion molecules, leading to the formation of transsynaptic adhesion molecules

Journal of basic and clinical physiology and pharmacology

Headaches: Reported at rates slightly above placebo, headaches can often be attributed to dehydration or rapid dietary changes rather than direct pharmacological effects

Seltzer MJ, Bennett BD, Joshi AD, Gao P, Thomas AG, Ferraris DV, Tsukamoto T, Rojas CJ, Slusher BS, Rabinowitz JD, et al

There were two abstentions