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Similarly, in breast cancer, LOH at this locus occurred in approximately 36% of breast cancer tissues, and GPx1 with a leucine-containing allele exhibited lower GPx1 activities in response to stimulation than GPx1 a proline-containing allele [88]

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Apigenin induces caspase-dependent apoptosis by inhibiting signal transducer and activator of transcription 3 signalling in HER2-overexpressing SKBR3 breast cancer cells