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The synergy rationale extrapolates from: (1) documented synergy between GHRH and various GHRPs (particularly GHRP-6) across multiple species and systems, (2) individual characterization of CJC-1295 No DAC showing 49-fold potency enhancement, (3) individual characterization of Ipamorelin showing comparable potency to GHRP-6 but with superior selectivity, and (4) established mechanistic principles of complementary receptor pathway activation
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[PMC free article: PMC3226010] [PubMed: 22105169] 150
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