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C., Sarwer, D

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By slowing down the process of gastric emptying, semaglutide lowers appetite and food consumption

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Both Use Gradual Dosing, But Tirzepatide Offers More Flexibility Semaglutide uses a fixed, stepup approach: Treatment begins with a low starting dose, which is gradually increased over several weeks

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The STEP 1 extension study followed participants who discontinued treatment after 68 weeks

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Most patients need 6+ months to see meaningful results, which puts total cost in the $5,400 to $6,000 range for weight loss alone, with no guarantee results hold after stopping This is one of the main reasons patients eventually explore a one-time surgical option instead of an indefinite monthly medication cost

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