Adems, las neuronas del NTS, que recogen aferencias de origen perifrico, sintetizan pre-proglucagn y son fuente de GLP-1 en el propio SNC, que alcanza mediante vas neuronales receptores especficos localizados en estructuras clave en el control de la ingesta, como el ncleo paraventricular, el septo lateral, el ncleo accumbens y el ncleo parabraquial lateral2,3,6
A true generic contains the same active ingredient as the brand, in the same form, and has to pass a bioequivalence review before a regulator approves it
They present numerous benefits, such as improved catalytic efficiency, resistance to harsh environments, prolonged effectiveness, and precise targeting
Larsson A, Ristoff E, Anderson ME: Glutathione synthetase deficiency and other disorders of the gamma-glutamyl cycle
Both compounds are widely discussed as causing nausea and other GI effects during dose escalation