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Proc Natl Acad Sci USA 103(4):962967

Reduced L-Glutathione is the glutathione form commonly abbreviated to GSH

The imbalance between production and quenching of these reactive substances through antioxidant mechanisms causes oxidative stress

While various risk factors for enhanced APAP toxicity have emerged in the numerous experimental models of steatosis, including induction of Cyp2E1, reduced phase II metabolism, mitochondrial dysfunction, etc., opposite effects have also been described, suggesting that steatosis may not affect toxicity [180]

Enhance the expression of osteogenic markers Osteocalcin (OC): Upregulates OC mRNA and protein expression by 20% -30%