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Those who dont have a B12 deficiency may not notice much of a change because their bodies will flush out the extra B12

Body aches and muscle pain affect some users, while others report joint pain that may be related to rapid weight loss and the biomechanical adjustments that come with it rather than the compound itself

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And even after people enroll, Milne wrote in an email to Undark, the substances short half-life would make it difficult for the researchers to ensure that participants are sticking with the trial protocol and not supplementing with gray market BPC-157

However, some research protocols use IM injection near the injury site for localized delivery with potentially higher local concentrations