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The oncogene K-Ras activates Nrf2 transcription through the Mek-Erk-Jun signaling pathway and reduces the ROS levels in primary fibroblasts

Mol Med 14:599607 Sathyapalan T, Beckett S, Rigby AS et al (2010) High cocoa polyphenol rich chocolate may reduce the burden of the symptoms in chronic fatigue syndrome

Parkin-mediated polyubiquitination then facilitates the interaction with autophagy receptors, ultimately leading to autophagosome formation and lysosomal degradation of dysfunctional mitochondria

Cell growth was allowed to proceed for 3 days after infection

Diosgenin protects retinal pigment epithelial cells from inflammatory damage and oxidative stress induced by high glucose by activating AMPK/Nrf2/HO-1 pathway