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Consistently, in a more recent, updated meta-analysis of eight CVOTs, GLP-1RAs reduced the risk of fatal or non-fatal stroke by 17% [3]

Semaglutide is contraindicated in patients with: Personal or family history of medullary thyroid carcinoma (MTC) Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Common Adverse Effects According to clinical trial data, gastrointestinal effects are most frequently reported: nausea, vomiting, diarrhea, constipation, and abdominal discomfort

This usually does not matter clinically, but it is another reason to store properly and not stretch vials beyond their labeled expiration

Apply light pressure for a few seconds, but dont rub the area to avoid irritation

Making an informed decision requires understanding both the potential benefits and significant risks involved