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What the Research Says About Muscle Loss on Ozempic Recent studies have measured how much lean body mass (which includes muscle) people lose while taking GLP-1 medications like Ozempic: A systematic review of 1,541 adults found that while semaglutide led to substantial fat loss, up to ~40% of the weight lost came from lean mass in some trials ( PubMed )

Its important to rotate injection sites to prevent skin irritation, for example, alternate between left and right abdomen or different areas of the thigh each night

However, some patients discover that they require several weeks before any discernable weight loss occurs

Viljoen, Semaglutide versus dulaglutide once weekly in patients with type 2 diabetes (SUSTAIN 7): a randomised, open-label, phase 3b trial

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