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Description

It is endogenously biosynthesised in the liver and kidneys from lysine and methionine through a four-step pathway proceeding via trimethyllysine and gamma-butyrobetaine, the final hydroxylation being catalysed by gamma-butyrobetaine dioxygenase

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Acute kidney injury was graded according to the KDIGO classification [15]

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10.1016/j.yebeh.2019.07.016 72

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