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10.1002/ar.24378

This is one of the strongest arguments for staying at or near the 100 mcg per injection saturation dose rather than escalating higher

[DOI] [PMC free article] [PubMed] [Google Scholar] 123.Woolbright B.L., Jaeschke H

Also Read : Why Indian Skin Needs Its Own Sunscreen Language There is an optimal concentration range for effective skin uptake, as penetration tends to plateau beyond certain levels, while excessively high concentrations may increase the risk of irritation

Answer: No, they are sometimes combined with topical therapy to increase and quicken outcomes