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Manufacturer: Daiichi Sankyo Healthcare

Research dose/evidence: Some cosmetic studies show Acmella extract (the source of spilanthol) improves wrinkle appearance, but there are fewer large clinical trials than for retinoids or peptides (there never are with botanical extracts)

A deficiency in carnitine may harm cellular function and result in digestive issues like constipation ( People with intellectual and motor disabilities are more likely than the general population to have a carnitine deficiency

Red flag #6: Before-and-after photos that all look the same If every before photo is a glum, downcast, harsh-lit shot and every after is a smiling, well-lit, professionally-edited image, you are looking at photography tricks, not clinical results

By working with the team at Maryland Trim Clinic, patients receive the exact kind of evidence-based, compassionate care necessary for successful metabolic health management