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Such interaction between the ECM and the actin cytoskeleton through integrins allows integrins to maintain cytoskeletal organization, cell motility and intracellular-signaling pathways such as cell survival, cell shape, cell proliferation, and angiogenesis (Luo et al., 2007)

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Using them together would cause extreme gastrointestinal distress, dangerous drops in blood sugar (hypoglycemia), and severe nausea

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