FDG-PET imaging has revealed significant metabolic declines in the middle frontal lobe and lower parietal lobe of PD patients with mild cognitive impairment, compared to those without mild cognitive impairment [39]
doi: 10.1038/nm.2002 154 DornelesGPda SilvaIBoeiraMCValentiniDFonsecaSGDal LagoPet al
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Unmasking of Receptors some receptors have a masking protein covering the intracellular portion of a receptor, like the GPCR seen below for example