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As a result, the ETC functioning is disrupted, and ATP content becomes significantly depleted, which breaks down metabolic and ionic homeostasis and activates the degradative enzymes such as nucleases, proteases, and phospholipases [182, 188]

doi: 10.1016/j.cell.2013.05.039 10 Lpez-OtnCBlascoMAPartridgeLSerranoMKroemerG

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