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N = 161,798 after matching GLP-1RA vs diet/exercise consultation Median follow-up: 2 years Key result: Any obesity-associated cancer HR 0.59, 95% CI 0.53-0.67 Site-specific signals: Multiple myeloma HR 0.37 Pancreatic cancer HR 0.40 Endometrial cancer HR 0.42 Colorectal cancer HR 0.49 But remember: This is observational

Sulfur-containing amino acids in protein break down more slowly in this environment, creating hydrogen sulfide gas that produces the characteristic rotten-egg smell

Clearance rate above/below the release rate would lead to a lower trough concentration assuming dosing remains the same

The science is clear

doi: 10.3390/ijms22179616