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Unlike classical type 2 diabetes marked by insulin resistance, this phenotype, estimated to affect 25 million people in LMICs, is characterized by severe pancreatic -cell dysfunction with substantial deficits in insulin secretion, yet insulin sensitivity is preserved, and autoimmunity or ketoacidosis are absent [144]
Advances in Enzymology and Related Areas of Molecular Biology
It plays a pivotal role in enhancing insulin secretion from the pancreas, a process crucial for maintaining glucose homeostasis
Due to oxidative stress caused by iron and ferroptosis caused by excitatory amino acid synergy, a large number of clinical trials on anti-amino acid toxicity and antioxidative stress treatment have been conducted
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