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L.-G.Hernndez-PinedoN.CarrilloM.Del CerroM.Esteban-GarcaN.Trigo-DamasI.et al (2024)

Cortisol dysregulation also becomes more pronounced as estrogen withdrawal activates the HPA axis, producing the elevated baseline stress-hormone output that drives the "tired but wired" pattern common in midlife women

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These symptoms are worth mentioning to your dentist: Dry mouth that lingers throughout the day Bad breath that doesnt go away with brushing Bleeding, red, or swollen gums Sudden sensitivity to temperature or sweets Teeth that feel loose, shift slightly, or no longer fit together the same Cracks or chips without any clear cause These signs dont necessarily mean something serious is happening, but they do suggest your teeth and gums may need closer attention during treatment

If considering this, it may be prudent to separate berberine and probiotic doses by several hours given berberine's antimicrobial properties