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Accordingly, the downregulation of MMP-1, MMP-3 and MMP-13 expressions and the upregulation of TIMP-1 expression were reported due to the use of TQ in chondrocytes and cartilage in the animal model

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Bile is essential for detoxification, digestion, absorption of fats and fat-soluble vitamins, and many more important body functions (12)

Bacterial strains and culture Lactobacillus murinus freeze-dried powder (BeNa Culture Collection, Beijing, China) was dissolved in 25 ml of MRS broth (Hope Bio-Technology, Qingdao, China)