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Titration is the process of starting at a low dose and gradually increasing it to allow your digestive system to adapt

The good news is that nausea is strongly dose-related: the 2.5 mg starting dose produces much less nausea than the 1015 mg maintenance doses, and symptoms typically ease at each level as blood levels plateau over about four weeks

When administered as a once-weekly subcutaneous injection, tirzepatide binds to both GIP and GLP-1 receptors, triggering multiple metabolic effects throughout the body

The GLP-1 agonist drugs work by mimicking that hormone, helping to lower blood sugar while also making someone feel full

It is caused by rapid movement of food into the intestine, which pulls fluid from the bloodstream into the gut