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However, tricarboxylic acid enzymatic activity in leukocytes of recent-onset drug-nave people with BD in a depressive episode was not different from healthy participants [52]

The most common side effects with naltrexone are: Nausea Vomiting Headaches Fatigue Heightened Anxiety Abdominal Pain Dizziness Muscle pain Joint pain Constipation Diarrhea Appetite Loss Insomnia Sleep Disturbances Serious side effects that are much less likely include: Liver Damage Depression Allergic Reaction GLP-1 The side effects for GLP-1 medications are very similar to naltrexone

J Oral Biol Craniofac Res

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Your doctor can help determine whether libido changes represent a medication side effect, a consequence of rapid weight loss, an unrelated medical condition, or a combination of factors