Once the oxidative threat has passed and the cellular redox balance is restored, specialized enzymes such as glutaredoxin (Grx) or thioredoxin (Trx) carefully remove the glutathione cap, returning the protein to its normal, functional state
The first stage of the reaction included dsDNA (annealed H3/H4 dsDNA
Balkan Med J 33:188192
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Muneoka K, Kuwagata M, Ogawa T, Shioda S (2015) Mother/offspring co-administration of the traditional herbal remedy yokukansan during the nursing period influences grooming and cerebellar serotonin levels in a rat model of neurodevelopmental disorders