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79 HalarisA.PiletzJ

Dupilumab is a type of biologic drug called a monoclonal antibody

Hormonal imbalance

L -serine is converted to D -serine by serine racemase in astrocytes, regulating NMDA receptor activation via GluN1 subunits [315]

Given the essential role of glutamine supply in cancer cell proliferation and immune cell phenotypes, developing novel antitumor drugs targeting glutamine metabolism has shown promising therapeutic effects in various mouse cancer models and preclinical tests (Oh et al., 2020