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The liver stores 3 to 5 years worth of b12 under normal circumstances

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Ultimately, advancements in these areas will determine whether probiotics and related live biotherapeutics can transition from broadly categorized health-promoting supplements to precisely targeted, mechanism-based interventions that are incorporated into evidence-based guidelines for both prevention and treatment (294)

The potential health benefits of any B vitamins or B complex vitamins outweigh any potential risks, like bright yellow urine