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Staying on continuous GLP-1 therapy with PlexusDx prevents this rebound cycle by maintaining appetite suppression and metabolic benefits long-term

Use of drugs that inhibit organic cation transporter 1 activity (including tricyclic antidepressants, citalopram, proton-pump inhibitors, verapamil, diltiazem, doxazosin, spironolactone, clopidogrel, rosiglitazone, quinine, tramadol and codeine) increased intolerance to metformin (72)

Human pharmacokinetic values for semaglutide and tirzepatide included for mechanistic reference only

Ozempic, while primarily used to manage blood sugar levels in people with type 2 diabetes, can also impact other body systems

Ozempic, while originally FDA-approved for managing type 2 diabetes, is now increasingly prescribed off-label for weight loss in patients without diabetes