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The KRASG12C inhibitor MRTX849 provides insight toward therapeutic susceptibility of KRAS-Mutant cancers in mouse models and patients

Clinical Implications The growing prevalence of GLP-1 receptor agonist and dual incretin agonist use necessitates increased awareness among anesthesiologists, surgeons, gastroenterologists, endocrinologists, primary care clinicians, and perioperative nursing teams

2 In the REIMAGINE 3 trial, the most commonly reported AEs were GI-related, occurring in 51/90 (57%) participants in the CagriSema 2.4 mg/2.4 mg group, 42/93 (45%) participants in the CagriSema 1 mg/1 mg group, and 21/91 (23%) participants in the placebo group