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Unlike deficiency states, which produce well-characterised neurological and haematological symptoms, there is no clearly defined clinical syndrome associated with B12 excess from supplementation alone

You didn't go to sleep that long ago, but, you know, as far as your neuroendocrine system is concerned, it's like, "Oh, well, there's no more melatonin and, you know..." And so, there's a bit of a

Using proteomic approaches, SIR has been identified as a TRX target in wheat seeds (Wong et al., 2004) and in Synechocystis (Lindahl and Florencio, 2003)

Nature 560 (7719), 494498 (2018)

Strong AP, Haeusler S, Weatherall M, Krebs J (2016) Sublingual vitamin B12 compared to intramuscular injection in patients with type 2 diabetes treated with metformin: a randomized trial