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Combined with other serotonergic agents, it may trigger serotonin syndrome

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Translational scaling from animal studies, typically yielding estimates between 14 mcg/kg

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In one embodiment of the otic formulations or compositions described herein, the otic formulation or composition is provided as a thickened liquid formulation composition, also referred to herein as auris-acceptable thickened liquid formulation or composition, auris thickened liquid formulations or compositions or variations thereof