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Giugliano D, Chiodini P, Maiorino MI, Bellastella G, Esposito K

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During reverse topology fission, distal monolayer is exoplasmic, and proximal monolayer is cytoplasmic (Figure 1)

As mentioned above, the ability of GLP-1 to regulate cholesterol metabolism and the fact that GLP-1 circulates between the CNS and systemic metabolism suggest that GLP-1 is an important target in the treatment of cerebrovascular diseases in terms of altered cholesterol metabolism and vascular dysfunction