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Patients in the highest quartile of GPx1 activity had a hazard ratio of 0.29 (95% CI, 0.150.58) compared to those in the lowest quartile [86]

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Metformin prevents dopaminergic neuron death in MPTP/P-induced mouse model of parkinsons disease via autophagy and mitochondrial ROS clearance

Some research suggests that chronic high-dose L-carnitine supplementation may increase TMAO levels via gut bacteria metabolism, and elevated TMAO has been associated with increased cardiovascular risk in observational studies