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Look for HPLC purity testing and mass spectrometry confirmation of the correct molecular weight

G., Glutamate Induces the Production of Reactive Oxygen Species in Cultured Forebrain Neurons Following NMDA Receptor Activation, Journal of Neuroscience 15 (1995): 33183327, 10.1523/jneurosci.15-05-03318.1995

It can mean more binding protein in circulation, vitamin released from injured cells, reduced clearance by the liver or kidneys, recent intake, or analytical interference, where the measured value does not accurately reflect the true B12 status

This reduces the drugs bioavailability, the amount of the drug that reaches the target site

So we're sort of turning those back on