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This extended duration is what allows it to be administered as a once-weekly injection

Most common AEs were gastrointestinal, and of mild or moderate severity (Table 2)

Accordingly, the sterility of the needles cannot be confirmed, which presents an increased risk of infection for patients who use the counterfeit products

Here, v/v 20% piperidine/DMF is a mixture of 20% piperidine by mass and 80% DMF by mass, and is only one deprotecting agent, and other deprotecting agents such as 1% DBU/DMF solution (DBU is 1, 8-diazacyclo [5,4,0] -7 undecene), and 5% piperazine/DMF solution may be used

Ketogenic diet in mitochondrial diseases Mitochondrial diseases are systemic and heterogenic diseases caused by underlying pathogenic variants in nuclear or mitochondrial DNA (mtDNA)