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Contrarily, generally no new vessels grew in BPC 157treated rats (i.e., those that did form in the limbus did not make contact with the penetrated area) (Masnec et al., 2015), showing that BPC 157 therapy may acknowledge also the angiogenic privilege of the corneal avascularity as essential for corneal wound healing (Tshionyi et al., 2012)

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Chronic deficiency may result in weight loss, loss of appetite, and digestive issues

However, absence of thorough human clinical trial data means some uncertainty remains regarding long-term safety