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Novo Nordisk (the makers of Ozempic and Wegovy) funded a large, randomized, controlled, and double-blinded study designed to answer that open questionthe SELECT trial

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Adjustments can include slowing the titration schedule, increasing the pyridoxine component, adding ondansetron for breakthrough nausea, or switching to a different GLP-1 medication if semaglutide fundamentally does not agree with your system

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