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In addition, cystinotic cells exposed to oxidative stress (hydrogen peroxide) were unable to increase their GSH concentration above baseline

However, another group found spironolactone to mitigate RN after internal alpha-particle irradiation in mice [101]

It is not known whether GSH could be involved more directly in S

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Furthermore, by binding with heavy metals, pesticides, and metabolic byproducts, glutathione reduces the liver's toxic load, protecting it from damage