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Deletion of GSH is a significant factor underpinning heightened OS in T2DM

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Its effects accumulate quietly over weeks

The data validation process included: Standardization of units (currency conversions, volume units, inflation adjustments) Cross-verification of data points across multiple secondary sources Normalization of inconsistent datasets Identification and resolution of data gaps Outlier detection and removal through algorithmic and manual checks Plausibility and coherence checks across segments and geographies This ensured that the dataset used for modelling was clean, robust, and reliable

For morphometric analysis of granuloma and immune cell infiltration, the H&E stained mice lung sections were analyzed using Path Scan Enabler-5 (Mayer Scientific, TX, United States) followed by morphometric determination of the area of lung involved in granulomatous response using Sigma Scan Pro (Systat Software Inc., CA, United States) as described previously ( Quantification of Glutathione Levels GSH levels were measured in the lung lysates of untreated, 40 mM L-GSH, RIF, and RIF +40 mM GSH treated diabetic mice at 4-weeks and 8-weeks post-infection