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284 MAT2A Methylthioadenosine phosphorylase (MTAP)-deficient tumors account for ~15% of solid tumors, including ~15% of NSCLC, 28% of esophageal cancer, 26% of bladder cancer, and 10% of esophagogastric cancer

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New techniques such as 3D and speckle-tracking echocardiography (STE) provide further insights into heart function, showing that Global Longitudinal Strain (GLS) may be a better prognostic indicator than EF (41)

Some patients may also experience fatigue or decreased appetite

The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat PMID: 12591111 Eur J Pharmacol