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This dual role enables Apaf-1 to coordinate the switch between apoptosis and inflammatory signaling, establishing it as a critical cell fate checkpoint (180)

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In spite of limitations to the generalizability of the current creatine finding, it suggests that investigators reporting creatine-normalized metabolites in AnxD studies also report appropriately water-normalized values or demonstrate equivalence of water-normalized creatine values in patients and controls

doi: 10.3390/cimb46030123 122 DaQRenMHuangLQuJYangQXuJet al