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Marimastat (BB-2516), a small molecule MMP inhibitor, has shown promise by enhancing the in vivo efficacy of INH and RFP, increasing the proportion of healthy blood vessels at the infection site, and enhancing drug delivery and retention [137]
Adrenal tumours typically require surgical adrenalectomy, whilst ectopic ACTH-secreting tumours necessitate identification and removal of the primary malignancy when feasible
Role of oxidative metabolism in the localization of plant viruses