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As a clinical necessity

From thioesters to amides and back: condensation domain reversibility in the biosynthesis of vibriobactin

The potential for impeccable results is high

The number and share of LIS enrollees in national PDPs vary considerably, which is related to the fact that only 1 of these 10 plans (Wellcare Classic) is a benchmark PDP in all 34 PDP regions, meaning it is available to all Part D enrollees receiving LIS for no premium (4 other PDPs are benchmark plans in some but not all regions) (Appendix Table 3)

For these localized applications, systemic absorption may matter less than direct contact with digestive tissues