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There is no known interaction between PDE5 inhibitors like sildenafil or tadalafil and GLP-1 medications, so they can be used together if you need short-term help with erections while your weight comes down

The derivatives were resolved and detected using liquid chromatography/electron spray ionization/tandem mass spectrometry in multi-reaction monitoring mode

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Additionally, both medications can affect appetite significantly, potentially leading to inadequate nutritional intake if not properly managed