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The opening of the LTCC contributes to the positive inotropic effect of isoprenaline, and when this opening is impaired by nifedipine, the positive inotropic effect of isoprenaline can be diminished
For example, the neurotoxin models of PD (using MPTP or 6-OHDA) recapitulate features of the diseaseelevated -synuclein, astrocyte activation, bloodbrain barrier disruption, inflammation, oxidative stress, and dopaminergic neuron lossand these models have demonstrated the neuroprotective potential of various dietary polyphenols (10)
M., Chen, M., Zhou, F
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