In STEP 1, up to 74% of participants reported nausea with semaglutide 2.4 mg, yet discontinuation for GI reasons was relatively low (4.5%) [3]
However, it has been shown that mortality is significantly decreased by the administration of NAC even up to 36 h after the toxic ingestion and that this cohort of patients is less likely to progress to grade III/IV hepatic coma after receiving treatment with NAC[69]
Pharmacies that do will assign longer, more accurate BUDs based on actual data rather than conservative USP defaults
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