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Could the improvements seen be due to gluten elimination

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Interestingly, bioinformatic analyses conducted on bulk tissue data obtained from healthy human brain tissue donors revealed that endothelial cells and microglia were the predominant senescent cell types, driven by CDKN1A/p21WAF1/CIP1 (42) revealing potential differences in senescent cell types between healthy and diseased states

Targeting glutamine metabolism in myeloproliferative neoplasms