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However, in a subanalysis of participants with low vitamin B 12 status at baseline (n= 101), the B-vitamin supplementation slowed the decline in bone mineral density (total hip and femoral neck but not lumbar spine) (116)

Functional validation using receptor-deficient models confirms that 3-adrenergic signaling is required for these effects, as disruption of this pathway attenuates peptide-induced lipolysis

Omega-3 fatty acids Data suggests that these anti-inflammatory fatty acid supplements are more effective for lowering triglycerides in postmenopausal women

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